A 2020-2024 Ford F-150 averages $1,124 a year in maintenance, or about $11,242 over 10 years - the highest 10-year total in ServiceSage's vehicle cost dataset - starting around $477 in year 1 and rising to about $1,670 by year 10. It carries a 32 percent chance of a major repair in the first 10 years and a reliability score of 3.0 out of 5, with the most expensive common repair being cam phaser/timing chain work at $1,500-$3,500.
Ford recommends 7,500-10,000 mile oil changes under normal duty, dropping to 5,000 miles under severe duty (towing/turbo). The 10R80 10-speed automatic's Mercon ULV fluid is rated for 150,000 miles normal duty (30,000-60,000 miles severe duty) and has no traditional dipstick - checking the level requires the transmission at 206-215 F and a plug on the passenger side of the case. Spark plugs run 100,000 miles normal duty or 50,000-60,000 miles severe duty; coolant is changed at 100,000 miles/6 years either way.